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Home>Products>Raw Steroid Powders>Pharmaceutical Grade Steroids Diuretic Spironolactone Powder 52-01-7
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Pharmaceutical Grade Steroids Diuretic Spironolactone Powder 52-01-7
- SBJ
52-01-7
- china manufactuer
- USP
- 10g
- Negotiable
- Special disguised packaging or as your
- within 12hours after payment
- Western Union,MoneyGram,T/T,Bitcoin
- plent of stock
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Zhuhaishi Shuangboyi Technology Co.,ltd2020-07-10 09:46:19
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Pharmaceutical Grade Steroids Diuretic Spironolactone Powder 52-01-7
Spironolactone
Spironolactone English name: Spironolactone
Spironolactone Synonym: Aldactone; Antisterone; Spirolactone; 7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21, 17-beta- carbolactone
Spironolactone CAS: 52-01-7
Spironolactone EINECS Number: 200-133-6
Spironolactone Formula: C24H32O4S
Spironolactone MW: 416.5735
Spironolactone Density: 1.24g / cm3
Spironolactone Melting point: 198-207 ℃ (dec.)
Spironolactone Boiling point: 597 ° C at 760 mmHg
Spironolactone Flash Point: 302.2 ° C
Spironolactone Water-soluble: practically insoluble
Spironolactone Vapor Pressure: 3.24E-14mmHg at 25 ° C
Spironolactone Melting point 198-207 ° C (dec.)
Spironolactone Specific rotation -37 ° (c = 1, CHCl3)
Spironolactone Water-soluble practically insoluble
Spironolactone Assay: 98.99%
Spironolactone Appearance: White or almost white fine crystalline powder
Spironolactone Uses: Used as a diuretic
| ITEMS | STANDARDS | RESULTS |
| Appearance (Ph.Eur.) | A white or yellowish-white powder | White powder |
| Solubility (Ph.Eur.) | Practically insoluble in water, soluble in ethanol (96%) | Complies |
| Identification | ||
| A. IR –spectrum (Ph.Eur.) | Meet the requirement | Complies |
| A. IR –spectrum (USP) | Meet the requirement | Complies |
| B. TLC (Ph.Eur.) | Meet the requirement | Complies |
| B. UV absorption (USP) | Meet the requirement | Complies |
| C. Colour reaction (Ph.Eur.) | Meet the requirement | Complies |
| C. Precipitate reaction (USP) | Meet the requirement | Complies |
| Specific optical rotation | -41°~-46° | -42.8° |
| (Ph.Eur.) | -41°~-45° | -42.9° |
| (USP) | ||
| Sulphated ash (Ph.Eur.) | ≤0.1% | 0.00% |
| Related substances (Ph.Eur.) | ||
| Impurity A | ≤0.2% | N.D. |
| Impurity B | ≤0.3% | N.D. |
| Impurity C | ≤0.2% | N.D. |
| Impurity D | ≤0.15% | N.D. |
| Impurity E | ≤0.3% | N.D. |
| Impurity I | ≤0.5% | 0.05% |
| Any unspecified impurity | ≤0.10% | Complies |
| Total | ≤0.7% | 0.13% |
| Ordinary impurities (USP) | ≤2.0% | Complies |
| Free thiol compounds (Ph.Eur.) | ≤0.05mL | Complies |
| Free mercapto compounds (USP) | ≤0.10mL | Complies |
| Chromium (Ph.Eur.) | ≤50ppm | Complies |
| Assay | 97.5%~102.0% | 100.90% |
| HPLC (Ph.Eur.) | 97.5%~103.0% | 99.60% |
| HPLC (USP) | ||
| Residual solvent (In-house) | ≤3000ppm | 90ppm |
| Methanol | ≤720ppm | ≤LOD (0.0046ppm) |
| Tetrahydrofuran | ≤880ppm | ≤LOD (0.23ppm) |
| DMF | ||
| Particle size (In-house) | 95% ≤ 20 microns | Complies |
| Conclusion | Compiles with EP7/USP35 | |
Description
Spironolactone and commonly shortened simply to "spiro") ,marketed mainly under the brand name.
Aldactone in most countries, is a synthetic, steroidal antimineralocorticoid, antiandrogen, and, to a lesser extent, progestin. It belongs to a class of pharmaceutical drugs known as potassium-sparing diuretics, and is used primarily as a diuretic and antihypertensive in the treatment of heart failure andhypertension. As a secondary use, spironolactone is also frequently employed off-label for the purpose of reducing elevated or unwanted androgen levels and activity in the body, such as in the treatment of hyperandrogenism in women and, especially, as a component of hormone replacement therapy for trans women.
Applications
Spironolactone is competitive inhibition of aldosterone drugs, drug itself is not active, role is diuresis and endogenous competitive aldosterone antagonist and happen, belongs to the potassium diuretics.
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The Information You Want To Know
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About us
Zhuhaishi Shuangbojie Technology Co., Ltd, a leading manufacturer and supplier of fine chemicals in China, is located in Zhuhai City Guangdong Province. Our company's various chemical raw material products have stable and reliable quality, it is mainly sold to pharmacy company and health care company in abroad, like USA, Canada, UK,
Brazil, Netherlands, Ireland, New Zealand, Austria, Australia and so on.
Our company will take highquality products, the most preferential prices and the most considerate service for your satisfaction. We look forward to opportunities for business cooperation with you.
Contact Us
- Zhuhaishi Shuangboyi Technology Co.,ltd
- AddressYuehai International Garden,Zhuhai City,Guangdong Province,519000
- Phone(Working Time)86-18578209858
- Fax86-18578209857
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